Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy
...Published in Proceedings of the National Academy of Sciences
Mesenchymal stem cells (MSCs) are multipotent progenitor cells with the ability to differentiate into multiple mesoderm lineages in the course of normal tissue homeostasis or during injury. We have previously shown that MSCs migrate to sites of tumorigenesis, where they become activated by cancer cells to promote metastasis. However, the molecular ...