Specific antiviral activities of the human cz interferons are determined at the level of receptor (IFNAR) structure
Published in FEBS Letters
Differences in activity among the family of human IFNs a are much reduced if these ligands are assayed on bovine ceils. In particular, the activity of IFN ctD is much higher on bovine than on human cells. To examine these differences, the bovine counterpart of the human IFNAR has been cloned and expressed in a human cell line. The transfected cell ...